Bruker Daltonics introduces new Maldi Molecular Imager for in-vitro imaging of protein biomarkers

By E. Janene Geiss

Philadelphia, March 10 - Bruker Daltonics announced Friday the release of its novel Maldi Molecular Imager, a system for in-vitro imaging of peptide and protein biomarker distributions in tissue sections and cell clusters, including tumor regions.

The Maldi Molecular Imager addresses the need for high-sensitivity imaging of the spatial distribution of protein biomarkers in biological, pathology and other clinical research, officials said in a news release.

The imager uses an easy-to-use autoFlex Maldi-Tof mass spectrometer equipped with proprietary smartbeam laser technology for high-throughput Maldi Imaging, officials said.

The technology also incorporates powerful flex imaging visualization and image processing software, and further expands Bruker Daltonics' leading Clinprot product line for clinical proteomics and protein biomarker analysis, officials said.

The imager can be applied whenever tissue sections are used to evaluate cellular histology and to monitor the spatial distribution of biomarkers in pathology, morphology, oncology or neurology, and many other clinical research fields, officials said.

"Biomarker discovery will benefit enormously from the direct analysis of tissue sections by Maldi-MS. Gaining knowledge about the spatial localization of proteins and compounds in tissue will also provide invaluable knowledge to drug candidate research and chemical compound monitoring in animal and plant tissue," Richard M. Caprioli, director of Mass Spectrometry Research Center at the Vanderbilt University Medical Center in Nashville, Tenn., and the first customer of the technology, said in the release.

The imager will be exhibited at Pittcon 2006, the 57th Pittsburgh Conference and Exposition on Analytical Chemistry and Applied Spectroscopy to be held next week in Orlando, Fla.

Bruker BioSciences, based in Billerica, Mass., is the publicly traded parent company of Bruker Daltonics Inc. and Bruker AXS Inc. Bruker AXS is a developer and provider of life science, materials research and industrial X-ray analysis tools. Bruker Daltonics is a developer and provider of innovative life science tools based on mass spectrometry. Bruker Daltonics also offers nuclear, biological and chemical detection products for defense and homeland security.

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