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Northwest Biotherapeutics signs Synteract to manage phase 2 trial of DCVax-Brain
By Lisa Kerner
Charlotte, N.C., Aug. 15 - Northwest Biotherapeutics, Inc. awarded a clinical trial management contract to Synteract to manage its phase 2 trial evaluating DCVax-Brain in patients with Glioblastoma multiforme.
DCVax-Brain uses the patient's own dendritic cells (immune cells) with the patient's own tumor biomarkers (antigens), according to a company news release.
The phase 2 trial is based on two phase 1 clinical trials that demonstrated that patient survival was more than twice as long for patients receiving DCVax-Brain treatment compared to two current Food and Drug Administration-approved therapies.
Northwest is a Bothell, Wash., biotechnology company focused on immunotherapy products for the treatment of cancer.
Synteract is a privately held, contract research organization based in Carlsbad, Calif.
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