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Bayer signs blood immunoassay licensing agreement with Signet Labs
By Ted A. Knutson
Washington, March 1 - Bayer HealthCare LLC, Diagnostics Division, a member of the Bayer Group, said Wednesday it has signed a licensing agreement with Signet Laboratories, Inc.
The agreement provides that Signet will conduct research with immunoassays discovered by Bayer scientists that detect two markers of inflammation, uristatin (Uri) and bikunin (Bik), found in blood and urine.
Signet plans to offer assays to investigators conducting research into the detection and management of acute and chronic diseases.
Acute inflammation can result from sepsis, meningitis, respiratory infection, urinary tract infection, viral infection, and bacterial infection. Chronic inflammation is often associated with diabetes mellitus, acute myocardial infarction, coronary artery disease, kidney diseases, and certain auto-immune disorders, such as rheumatoid arthritis and organ failure.
"The trypsin inhibitors Uri and Bik are cutting-edge biomarkers that can have a great impact on the diagnosis and management of diseases for inflammation, such as kidney disease," said Dr. Michael Pugia, director of Urinalysis R&D, Bayer Diagnostics, in a press release. "We are confident that with Signet's expertise in developing important immunoassays for medical researchers, these markers will one day improve and manage health in people affected by inflammatory diseases."
"Signet will evaluate the trypsin inhibitors as biomarkers for acute renal failure (ARF) with a view toward developing them into companion assays for our Nephroscreen, an RUO assay that may predict the onset of ARF," said Dr. Peggy Taylor, vice president of production and development for Signet, in the release.
Signet is a Dedham, Mass.-based biotechnology company.
Bayer HealthCare's parent company, Bayer AG, is a health care and medical products company based in Leverkusen, Germany.
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