Sigma-Aldrich expands Panorama Protein Array product line

By Ted A. Knutson

Washington, Feb. 23 - Sigma-Aldrich Corp. announced the addition of the Kinase v1 protein array to its Panorama Protein Array product line.

Developed in conjunction with Procognia Ltd. UK and licensed exclusively through Sigma-Aldrich, the Kinase v1 protein array contains 152 commonly studied kinases.

This array employs a unique fusion tag attached to each kinase that serves to tether and uniformly orientate proteins on the array surface and has been shown to confer kinase functionality.

Sigma-Aldrich said the technology offers the unique advantage that allows proteins to behave in a sterically unencumbered manner on the array and potentially result in more physiologically relevant data.

The company added the Panorama Human Kinase v1 Array extends its array portfolio for proteomic research, including arrays of proteins, antibodies, peptides and tissue extracts.

The firm explained that given the growing and pivotal importance of kinases in virtually every cellular function, a dire need has emerged among researchers to study the "kinome" in a multiplex array format. By providing a themed array of commonly studied kinases, researchers can study the function of this key protein family by performing multiplex assays for selectivity profiling with other proteins, antibodies, peptides, kinases and drug candidates.

Sigma-Aldrich is a St. Louis-based biotechnology company.

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