Salix study finds OsmoPrep liquid bowel cleanser superior

By Lisa Kerner

Erie, Pa., April 19 - Salix Pharmaceuticals, Ltd. said a study found a greater percentage of patients using its OsmoPrep tablets recorded a mean overall colon cleansing score of 'excellent' compared to patients who used HalfLytely with Bisacodyl Tablets Bowel Prep Kit.

Salix plans to launch OsmoPrep to physicians in June and will present two posters discussing OsmoPrep trial results at Digestive Disease Week 2006, May 20-25, in Los Angeles.

The primary endpoint of the study was the demonstration of colon cleansing efficacy of 48 gm (32 tablets) OsmoPrep compared to of 2 liters HalfLytely and Bisacodyl Tablets Bowel Prep Kit.

The multi-center, randomized, superiority trial involved 411 patients completing scheduled colonoscopy to compare the colon cleansing, patient tolerability, patient preference and safety profile of OsmoPrep to HalfLytely.

More than 10 million uses of bowel cleansing agents were prescribed during 2005, the company said.

Salix, located in Raleigh, N.C., develops and markets prescription pharmaceutical products for the treatment of gastrointestinal diseases.

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