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Published on 4/27/2006 in the Prospect News Biotech Daily.

Merrill has Onyx at neutral

Onyx Pharmaceuticals, Inc. remained at its neutral rating by Merrill Lynch analyst Eric Ende. Merrill expects positive survival data that could allow Sutent to gain a higher market share in firs-line metastatic kidney cancer, resulting in Nexavar gaining a higher second-line share. Phase 3 survival data for Sutent in kidney cancer compared to Interferon-a in front-line, metastatic kidney cancer patients will be presented at ASCO. Median survival analysis could be confounded by the high number of patients crossing over to the treatment arm. Nexavar data in melanoma and liver cancer may be available by the end of 2006. Shares of the Emeryville, Calif., biopharmaceutical company were up $0.65, or 2.85%, at $23.45 on volume of 1,058,100 shares versus the three-month running average of 687,289 shares. (Nasdaq: ONXX)


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