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Published on 11/23/2005 in the Prospect News Biotech Daily.

Kane's KBI-5898-coated urinary catheters show bacterial resistance

By Angela McDaniels

Seattle, Nov. 23 - Kane Biotech Inc. said an in vivo study showed that urinary catheters coated with the company's KBI-5898 were significantly less likely to be colonized by bacteria than either silver-hydrogel coated catheters, the current standard, or uncoated catheters.

Only 7% of catheter segments coated with KBI-5898 were colonized, compared to 89% of those coated with silver-hydrogel and 64% of uncoated catheters, the company said.

Furthermore, the study showed that only 4% of segments coated with KBI-5898 developed a catheter-related infection, as measured by testing for the presence of bacteria at the site surrounding the catheter. This compares to 43% of those coated with silver-hydrogel and 50% of uncoated catheters.

"These results visibly demonstrate the potential of our product to impact the occurrence of urinary tract infections, the single most common type of hospital acquired infection," vice president of business development Gord Froehlich said in a company news release.

Infections caused by urinary catheters cost the United Sates health care system more than $1 billion per year, the company said.

Kane Biotech is a biotechnology company based in Winnipeg, Man., that develops products to prevent and disperse bacterial biofilms.


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