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Boston Scientific: study shows benefits of dual-chamber pacing in implantable cardioverter defibrillators
By Lisa Kerner
Erie, Pa., May 22 - Boston Scientific Corp. said results of its Intrinsic RV study showed the majority of patients demonstrated the benefits of dual-chamber pacing with a lower risk of combined all-cause mortality and heart failure hospitalizations.
The multicenter, randomized clinical study of more than 1,500 patients was designed to study unnecessary pacing in recipients of an implantable cardioverter defibrillator (ICD), according to a company news release.
Known as "Inhibition of Unnecessary Right Ventricular Pacing with AV Search Hysteresis in ICDs (Intrinsic RV)," the trial randomized patients with mild and moderate pacing requirements to either atrial support pacing (DDDR+AVSH) or ventricular only pacing groups. Patients in the DDDR+ASH arm performed as well as patients programmed to ventricular only.
Intrinsic RV used Boston Scientific's AV Search Hysteresis (AVSH) technology that prevents right ventricular pacing if the heart's natural rhythm is detected.
"This trial highlights the importance of evidence-based medicine to further the understanding of advanced-feature medical devices, because Intrinsic RV actually refutes the notion that dual-chamber ICD programming poses an inherent safety risk," the co-principal investigator of Intrinsic RV, Brian Olshansky, said in the release.
"In fact, by using AV Search Hysteresis, outcomes with dual-chamber programming performed as well as, if not better, than single-chamber programming."
Natick, Mass.-based Boston Scientific develops, manufactures and markets medical devices used in interventional medical specialties.
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