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Published on 8/16/2006 in the Prospect News Biotech Daily.

Smith & Nephew: IDET analysis shows decrease in low back pain

By Elaine Rigoli

Tampa, Fla., Aug. 16 - A meta-analysis of Smith & Nephew's Intradiscal Electrothermal Therapy (IDET) procedure examining outcomes of 17 clinical studies demonstrates that patients suffering from chronic disc-related lower back pain experience a significant decrease in pain and improvement in physical function, as well as a low incidence of complications.

The company said study authors systematically synthesized all peer-reviewed published literature describing outcomes following the IDET procedure involving more than 500 patients.

The majority of clinical studies reported outcomes assessed from six to 24 months post-treatment.

The collective study results provide compelling evidence that the IDET procedure can significantly improve the quality of life for patients who suffer from chronic disc-related low back pain and are seeking relief, study authors noted.

Based on the meta-analysis, the review concludes that a statistically significant decrease in pain is reported post-treatment. Statistically significant improvements in physical function were also recorded. These improvements following the IDET procedure were accompanied by a low incidence of complications.

A meta-analysis is a statistical method that combines the results of several independent clinical trials. By integrating the body of evidence for a procedure, a meta-analysis allows for a more objective appraisal of the data and can also contribute to considerations about the consistency of the study results.

This study is published in the July/August issue of Pain Medicine, the peer-reviewed journal of the American Academy of Pain Medicine.

Smith & Nephew is a medical-technology business with headquarters in Andover, Mass.


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