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Published on 5/4/2006 in the Prospect News Biotech Daily.

Ligand releases positive data on Avinza for pain reduction

By Elaine Rigoli

Tampa, Fla., May 4 - Ligand Pharmaceuticals, Inc. announced the final data from three studies of its pain product Avinza that indicated the product showed better around-the-clock control of chronic pain and improved sleep in a large randomized study comparing Avinza given once daily to oxycodone CR given twice daily in patients with low back pain.

A second study demonstrated Avinza's ability to provide better sleep as well as improved pain control for patients with moderate-to-severe chronic osteoarthritis, according to a news release.

In the third study conducted in patients with chronic, non-cancer, moderate-to-severe pain, Avinza was shown to improve pain, sleep and physical functioning, the release said.

Avinza is a once-a-day treatment for chronic moderate-to-severe pain in patients who require continuous, around-the-clock opioid therapy for an extended period of time.

San Diego-based Ligand develops drugs in the areas of cancer, pain, skin diseases, hormone-related diseases, osteoporosis, metabolic disorders and cardiovascular and inflammatory diseases.


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