Lifeline Therapeutics: Data shows Protandim reduces oxidative stress

By E. Janene Geiss

Philadelphia, Jan. 17 - Lifeline Therapeutics, Inc. said Tuesday that data from a human study showed Protandim was able to reduce oxidative stress in men and women.

Oxidative stress results when the balance between oxidants and antioxidant enzymes is upset. Oxidative stress, which many authorities believe is central to the cellular aging process, increases as people age. There are more than a thousand scientific research studies indicating that high oxidative stress is associated with various diseases, according to a company news release.

Protandim, a patent-pending dietary supplement product consisting of five naturally occurring plant ingredients, significantly reduced harmful oxidants by inducing the body to produce more of its own antioxidant enzymes, officials said.

The study measured the levels of thiobarbituric acid-reactive substances, harmful substances created when cells are damaged by oxidation, in 29 subjects.

People taking Protandim experienced reduced oxidative stress as demonstrated by reducing the amount of thiobarbituric acid-reactive substances circulating in the blood by an average of 40%. This reduced oxidative stress occurred as a result of significantly increasing the activity of antioxidant enzymes that naturally help regulate healthy oxidative balance, officials said.

"These results represent a whole new approach to antioxidant therapy," senior study author Joe M. McCord, professor of medicine at the University of Colorado Denver Health Sciences Center, said in the release.

"Our review of the literature has found that studies with traditional antioxidant compounds have failed to eliminate the age-related increase in oxidative stress that we have seen in this study, suggesting that Protandim may offer a much more efficient way to reduce oxidative stress," he added.

The data was published in a January edition of the the scientific journal, Free Radical Biology & Medicine.

Lifeline Therapeutics is a Denver, Colo., publicly traded company that markets Protandim, a patent-pending dietary supplement that increases the body's natural antioxidant protection.

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