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Published on 9/15/2005 in the Prospect News Biotech Daily.

GTx plans follow-on sale of 5 million shares via Goldman Sachs

By Ronda Fears

Nashville, Sept. 15 - Men's health biotech research firm GTx Inc. announced plans to sell 5 million shares of common stock in an underwritten offering off the shelf via bookrunner Goldman Sachs & Co.

Lazard Capital Markets and SG Cowen & Co. are co-managers.

There is a greenshoe of 750,000 shares available.

Memphis-based GTx is focused on discovery treatments for prostate cancer and other serious health issues that affect men. Its lead research is centered on small molecules that selectively modulate the effects of estrogens and androgens, two essential classes of hormones. GTx currently has four clinical programs under way.

On Wednesday, GTx said it agrees with and will implement recommendations from the Food and Drug Administration relating to a pivotal late-stage trial of its Acapodene, in development for the prevention of prostate cancer in high-risk men.

The phase III trial will be evaluated at 36 months, with an interim evaluation at 24 months. If a sufficient reduction in prostate cancer at 24 months is achieved, GTx said it could potentially file a new drug application based on that data.

GTx stock closed at $10.34 on Thursday - and was seen plunging to $8.25 in after-hours trading.


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