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GlaxoSmithKline's Lamictal decreases seizures in adolescents, study says
By Elaine Rigoli
Tampa, Fla., Aug. 1 - Data published in the journal Pediatrics suggests that GlaxoSmithKline's lamotrigine (Lamictal) is an effective add-on therapy for the treatment of primary generalized tonic-clonic seizures in a subgroup of children and adolescents.
This randomized, double-blind clinical trial of primary generalized tonic-clonic seizures focused on patients between the ages of two and 20 and showed that Lamictal decreased seizures by 77% versus 40% in the placebo group.
The company said primary generalized tonic-clonic seizures, also known as "grand mal" seizures, are the most common form of generalized seizures, occurring in about 20% of patients with epilepsy. Lamictal is not currently indicated for the treatment of these seizures.
GlaxoSmithKline is a global pharmaceutical company based in London.
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